Copper(II) Complexes as Potential Antibacterial Agents

Muhammad Naeem Iqbal; Asfa Ashraf

نویسندگان

Muhammad Naeem Iqbal The School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Pakistan Science Mission (PSM), Narowal (Noor Kot 51770), Pakistan.
Asfa Ashraf The School of Life Sciences, Fujian Normal University, Fuzhou 350117, China; Pakistan Science Mission (PSM), Narowal (Noor Kot 51770), Pakistan.

کلمات کلیدی:

Cu(II) complexes, Staphylococcus aureus, Bacillus spizizenii, Escherichia coli, Klebsiella pneumonia.

چکیده

There is increasing interest in the use of copper (Cu)-containing complexes to combat bacterial infections. The antibacterial potential of two copper(II) complexes namely, (+) -(S)-2-(6-Methoxynaphthalen-2-yl) propanoic acid (Naproxen) and N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide (nimesulide) was studied against a range of medically significant pathogens, including Staphylococcus aureus, Bacillus spizizenii, Escherichia coli, and Klebsiella pneumonia. The antimicrobial assay showed that the complexes are active against S. aureus and B. spizizenii, E. coli and K. pneumonia. Hence, complexes possess biological activities and can be used to treat medically significant pathogens.