SARS-CoV-2: Resurgence of an Old Companion of SARS-CoV

Resurgence of Novel SARS-CoV-2

Abstract

Some of the emergent viral diseases pose a serious threat to humans as these come with limited treatment possibilities and occasionally prove to be extremely contagious resulting in high mortality ratio. Lately, in December 2019, a new coronavirus “Severe Acute Respiratory Syndrome Coronavirus 2” (SARS-CoV-2) evolved in Wuhan, China representing close similarity with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS-CoV) witnessed in the last two decades. Seeing the recent development of 2^nd wave of coronavirus in many parts of the world, it has become a pre-requisite to consider a detailed comparison of the coronavirus family to not only find the main origin but also the production of the functional vaccine as affected cases and mortality rates have soared much higher by this deadly virus. Since the final declared vaccine or therapy has not come into the market, we need to focus on the preventive measures at present. Up till now, numerous articles have been published on SARS-CoV-2 but the present review attempts to focus on more targeted information for comparisons of epidemiology, transmission, clinical features, risk factors, diagnosis, and treatment options for SARS-CoV, MERS-CoV, and SARS-CoV-2 for the future reference and treatment options.