Nano-Carriers Based Combating Approach against Antibiotic Resistance: An Insight into Nanoparticles Based Peptide Delivery

Abstract

Antibiotic resistance is the harbinger of a catastrophe for the globe in health point of view. Microbial resistances are emerging continuously and are causing life loss. Scientists and researchers are taking actions against this wildfire. Many medications and preventative strategies have been recommended to tackle this situation. In this regard, nanoparticles based medication came up with a new game plan. Nanoparticles are ideal due to their size, surface interaction, encapsulating drugs, targeted actions and stable delivery. Encapsulated peptide nanoparticles showed a new phase of drug delivery. Peptides are small sequences of amino acids, which upon delivery into the host cells proved to be fatal for resistant bacteria. These peptides can be the good candidate for medication and can be the alternative of antibiotics. However, natural peptides have some flaws regarding efficient actions; scientists are looking for synthetic peptides. Few studies have been conducted in this regard. This article focuses on the comprehensive review of antibiotic resistance and nano-carriers based therapy, which could be the ray of hope for the scientists against microbial resistance.